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Importance of Genetic testing (PGT) of embryos for abnormalities

Importance of Genetic testing (PGT) of embryos for abnormalities

Our breakthrough is preimplantation genetic screening (PGT-A) of embryos for abnormalities.

#PGT offers voluble insights into the genetic composition of embryos

Helping couples make informed decisions & significantly improving the chances of a successful pregnancy.

#Here we will explore the importance of genetic testing (PGT) of embryos for abnormalities & its numerous benefits

(PGT)

(PREIMPLANTATION GENETIC SCREENING ) / TESTING

It allows the selection of embryos with the highest likelihood of developing into the healthy pregnancies by screening for chromosomal abnormalities.

Detecting Genetic Abnormalities:-

It enables the identification of chromosomal abnormalities such as aneuploidy or structural rearrangements.This information helps determine the viability and health of embryos before they are transferred into the uterus.
Reducing the Risk of Genetic Disorder:-
Improving Success Rates of Assisted Reproductive :- By selecting embryos with the correct number of structure of chromosomes, PGT enhances the success rates of assisted reproductive technologies. (ART) such as an IVF.
Ethical Considerations Includes:

Handling of excess embryos

Psychological impact of screening for certain conditions

Embryo Biopsy Genetic Testing Methods Result Analysis
Few cells are carefully extracted from each embryo for genetic testing. Includes (NGS) Next generation sequencing or (PCR).
Occurs on 3rd day after fertilization or during blastocyst stage.    

Day 3 Embryo Biopsy

Day 5 Embryo Biopsy

PGT Limitations
Its important to acknowledge its limitations:
  1. PGT does not guarantee the birth of a healthy baby, as it cannot detect all genetic abnormalities or address mom – genetic factors that may affect pregnancy.

    So, there is still 1% risk of abnormalities in baby.

  2. False +VE or False –VE results can occur, leading to incorrect interpretations of embryo viability.
CONCLUSION:
By leveraging the power of genetic testing, couples can increase their chances of achieving a healthy pregnancy and welcoming a child into the world.

Fallopian tubes  &  Fertility 

Fallopian tubes  &  Fertility 

Your fallopian tubes play a vital role in the fertilization process necessary to become pregnant. The fallopian tubes are where the egg & sperm meet & the egg is fertilized.

The egg then travels through the fallopian fertilized. The egg then travels through the fallopian fertilized. The egg then travels through the fallopian tube , into the uterus to implant & grow into a baby.

So, lets address some questions are in one go:-

Can I get pregnant with only one working fallopian tube
A blockage can be in one or both fallopian tubes when , when a blockage exists , sperm cannot reach a viable egg waiting in the fallopian tube to become fertilized.
There are few options if you want to get pregnant after libel ligation.
Fertility with no fallopian tubes :-
There have been cases where women with no fallopian tubes are looking to become pregnant.
A women may have had her fallopian tubes removed for various reasons including:-
Why REVIVA Fertility & IVF Clinic

REVIVA Fertility & IVF Clinic is home to Chandigarh renowned fertility specialists. We custom design fertility treatments for the individual to increase the chances of a successful pregnancy.

Our specialist believe in putting the patient first and being with them through every step of the fertility journey. Our team is well versed in helping women of all ages reach their fertility goals and we are passionate about educating & supporting our patients throughout their journey .

Call us at 8288028667 or schedule your initial consultation today.

How to prepare yourself for blastocyst transfer

How to prepare yourself for blastocyst transfer

With the aid of ART, such as IVF , infertile intended parents can have children. We have came up with the best and easiest solution for you . I ensure after reading this blog all queries related to blastocyst transfer would be solved.

What does blastocyst transfer signify?

Blastocyst transfer will be briefly defined before the direct question is addressed. Embryos can be successfully cultured upto the blastocyst stage thanks to recent improvements in the IVF lab procedures and culture material. Compared to the embryos at an earlier stage,blastocyst might have higher chance of implanting into the uterine wall.

Blastocyst embryo transfer recommended for?

Blastocyst culture is being given as an alternative option to couples. Who have trial IVF or IVF-ICSI unsuccessfully despite having several high quality eggs recovered?

Couples that are strong candidates for blastocyst culture include those who have several healthy embryos on day 3.

How does transferring blastocyst benefits you?

  • A developing embryo generally exists the fallopian tube and enters the uterus at the blastocyst stage (5 days after fertilization).
  • The blastocyst begins to implant itself to the uterus lining once it has reached the uterus a practice called as implantation.
  • The benefit of trying to develop embryos to the blastocyst is that since this stage of development is more compatible with uterine environment. It should increase the likelihood that the embryos will implant; fewer embryos will need to be replaced as a result lowering the possibility of having multiple pregnancies.
Risks involved in blastocyst transfer:-
Drawbacks are that very few embryos (probably between 30% & 50% of them) will survive or develop to this stage. A 10% chance exists that no embryos will develop to the blastocyst transfer stage leaving no embryos eligible for transfer.There are also a lot fewer “spare” embryos available for freezing.
FINAL OUTCOME.
Our IVF expert dr sandeep cheema sohi will take excellent care of you. If you want to have a word with her, schedule an appointment with the best IVF centre in CHD just by making one phone call at 8288028667 or send your enquiry via an email at revivaclinic3@gmail.com

Bleeding & Spotting During ovulation: – When to be concerned

Bleeding & Spotting During ovulation: – When to be concerned

Ovulation occurs when the ovary releases an egg and some women experience bleeding & spotting around the time they are ovulating, which is normal occurrence. In fact, it’s fairly common for women to spot or bleed some point in their menstrual cycles. But when should you be concerned about the bleeding during ovulation?

( This blog post will explore the signs that indicate when ovulation spotting or bleeding is normal and when it is a sign of concern. it will also discuss the next steps that you can take if you are concerned about bleeding & spotting during ovulation.)

What is ovulation spotting?

Light vaginal bleeding that can occurs during before or after ovulation. (Not every woman has spotting during ovulation).

Ovulation bleeding occurs when there is a change in hormone levels. For example: estrogen levels decreases before woman starts ovulating and as a results, this causes endometrial to shed.

You may also experience other symptoms of ovulation such as :-

When does ovulation bleeding occur?

When you are ovulating, an ovary releases an egg and this occurs in the middle of your menstrual cycle between 11-12 days after the first day of your last period. Women do not always ovulate on the same days, as it depends on the length of their cycle.

When is spotting during ovulation considered normal?

Some signs that can help you determine whether your bleeding during ovulation is normal or a cause for concern.

  • First of all, it’s essential to keep in mind that ovulation bleeding occurs only once during each cycle.
  • Before you start ovulating, you experience an increase in estrogen levels, which then drop after ovulation. As a results progesterone levels rise for 5 days.
  • The fluctuation in E2 & P4 is what causes ovulation spotting.
When bleeding during ovulation is a sign of concern?
Heavy, severe and prolonged bleeding, we recommend seeing a doctor to provide you with diagnosis.
SOME HEALTH CONDITIONS CAN CAUSE BLEEDING BETWEEN PERIODS:
Spotting between periods can also be a sign of infection. If you have a sexually transmitted infection (STI) such as gonorrhea and Chlamydia, you have a high chance of having light bleeding.

BOOK YOUR APPOINTMENT TODAY

If you have any concerns or want to learn more about your cycle,
book your appointment with our gynecologist toady or contact us at

Recurrent Implantation Failure (RIF)

Recurrent Implantation Failure (RIF)

recurrent implantations

 

 

 

Recurrent implantation failure refers to the inability of embryos to implant into uterine lining after repeated attempts at ART like IVF. Despite transferring healthy embryos, they fail to attach to the uterus and initiate a pregnancy.

Who can get recurrent implantation failure?

  • RIF can affect individuals or couples undergoing ART , partially IVF , it can occur in cases where the underlying cause remains unidentified.

Types of RIF:-

Early RIF : In this , embryo fail to implant shortly after being transferred into the uterus.

Late RIF:– In this type , when the embryos implant initially but result in early miscarriage or failed development soon after implantation.

Causes of RIF:-

  • Embryo related factors: Chromosomal Abnormalities (poor embryo quality).
  • Urine Factors: urine abnormalities or structural tissues – endometrial receptivity tissues , chronic endometriosis or infections.
  • Hormonal factors: Hormonal imbalances affecting the menstrual cycle-thyroid disorders or diabetes.
  • Lifestyle and environmental factors: Smoking or substance abuse –poor diet and nutrition – stress and excessive physical activity.

What are the symptoms of RIF?

The symptoms of RIF can vary from person to person

However , there might be Recurrent implantation failure refers to the inability of embryos to implant into uterine lining after repeated attempts at ART like IVF. Despite transferring healthy embryos, they fail to attach to the uterus and initiate a pregnancy.

Who can get recurrent implantation failure?

  • RIF can affect individuals or couples undergoing ART , partially IVF , it can occur in cases where the underlying cause remains unidentified.

Types of RIF:-

Early RIF : In this , embryo fail to implant shortly after being transferred into the uterus.

Late RIF:- In this type , when the embryos implant initially but result in early miscarriage or failed development soon after implantation.

Causes of RIF:-

  • Embryo related factors: Chromosomal Abnormalities (poor embryo quality).
  • Urine Factors: urine abnormalities or structural tissues – endometrial receptivity tissues , chronic endometriosis or infections.
  • Hormonal factors: Hormonal imbalances affecting the menstrual cycle-thyroid disorders or diabetes.
  • Lifestyle and environmental factors: Smoking or substance abuse –poor diet and nutrition – stress and excessive physical activity.

What are the symptoms of RIF?

The symptoms of RIF can vary from person to person

However , there might be no specific symptoms & the primary indication is the inability to achieve a successful pregnancy despite multiple  attempts at embryo transfer.

How is Recurrent Implantation failure diagnosed?

no specific symptoms & the primary indication is the inability to achieve a successful pregnancy despite multiple  attempts at embryo transfer.

How is Recurrent Implantation failure diagnosed?

 
embryo-biopsy
 

Treatment for RIF

  • Improving Embryo Quality:

     Optimizing the quality of embryos through advanced laboratory techniques.

  • Endometrial Receptivity Analysis:

    Assessing the best time for embryo transfer based on the women menstrual cycle and hormonal profile.

  • Uterine preparation:

    Administering hormonal medications to prepare the uterine lining for better embryo implantation.

  • Lifestyle changes:

Adopting a healthy lifestyle changes, including balanced diet , regular exercise and stress management.

CONCLUSION:
Recurrent implantation failure is a complex and challenging condition that affects individuals and couples seeking to expand their families through ART. Understanding the various causes, symptoms, diagnosis & treatment options is crucial in effectively
 
 
 
 

ENDOMETRIOSIS & FERTILITY : 3 Reasons for women to have hope

ENDOMETRIOSIS & FERTILITY : 3 Reasons for women to have hope

If you want to get pregnant and you are diagnosed with endometriosis, you might assume that all hope is lost. With the right treatment, you might get pregnant more easily than you think.

3 Reasons Not to Panic About Endometriosis:-

Reason 1

Reason 2

Reason 3

There are many treatments, depending on what’s right for you:

MACROSCOPIC

MICROSCOPIC

(Woman with macroscopic Disease may have lesions and scar tissue That can sometimes block the fallopian tube) This can make it difficult for an egg to make Its way into the uterus. (On the other hand women with endometriosis have completely normal but microscopic lesions. It may or ,may not affect fertility)
Conclusion
we have come quite a long way in understanding endometriosis how it offers fertility and how to treat it. Your chances of conceiving are better than they have ever been, so its worth looking into the many treatment options that are available.

Early symptoms & cause of PCOS

Early symptoms & cause of PCOS

Polycystic ovary syndrome is a very common hormonal condition in females which causes hormonal imbalance. The females suffering from this produce excess of male’s hormones which results in delayed periods.

To be exact, in PCOS your ovaries produced usually high levels of hormones known as androgens which causes your reproduction hormones to become imbalanced leading to erratic menstrual cycle, missed periods & unpredictable ovulation.

  • You don’t have to spend your precious time searching for details of this problem as today we will be sharing the causes & symptoms of PCOS as per our fertility specialist & guide you through this.

What are the symptoms of PCOS 

There is a possibility that you have PCOS & your body doesn’t represent any of the symptoms & on the other hand, some women start seeing symptoms around their first period itself.

Anyhow here are few prominent symptoms of PCOS 

As PCOS presents with a diverse array of symptoms, which can manifest differently each individual. The most typical signs are :

Irregular menstrual cycle :- ovulation might be uneven or irregular , or it may not occur at all, which can cause irregular menstrual periods or even a totally absence of a monthly cycle.

Elevated Androgens: – it can cause actual side effects, including acne excessive face & body hair growth and male – pattern baldness.

Weight : Those dealing with PCOS often encounter challenges in managing their weight, heightening the likelihood of obesity.

It is crucial to remember that not everyone with PCOS will necessarily have all the symptoms, and symptom intensity can vary greatly.

Navigating Treatment Options for PCOS: A Holistic Approach  

The PCOS treatment objectives include symptom relief, fertility improvement, and lowering the danger of long-term health issues.

Lifestyle Modifications: Following a healthy lifestyle can be exceptionally useful in managing PCOS. Through a well-balanced diet and steady physical activity, it is possible to improve insulin sensitivity, and establish regular menstrual cycles.

Fertility Interventions: Fertility Intervention, for example, Ovulation Induction , IUI or In Vitro Fertilization ( IVF ), might be prompted for those attempting to get pregnant depending upon various factors.

Conclusion  

In conclusion, PCOS is a complex hormonal condition with a range of symptoms and causes.By adopting a holistic approach that encompasses lifestyle changes, medications, and emotional support, individuals with PCOS can lead fulfilling lives and better navigate the challenges posed by this condition.For more Query or information regarding PCOS must visit us at Reviva fertility and IVF clinic in sec- 9 D CHD or contact us at 9915004407

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Fresh VS Frozen Embryo Transfers: An Explanation through Comparisons

Fresh VS Frozen Embryo Transfers: An Explanation through Comparisons

Fresh embryo transfers were the only option when In Vitro Fertilization (IVF) was initially introduced due to the limited progress in cryopreservation techniques.

Fresh & Frozen Embryo Transfers

However, over the past years, significant advancements in:

Nowadays Generally FET’s are preferred depending upon various factors: -

  • Age of couple
  • No of oocytes received
  • Quality of embryos
  • Hormonal parameters
  • Adequacy of endometrial lining

Fresh & Frozen Embryo Transfers

Understanding the Differences

Fresh Embryo Transfer

Frozen Embryo Transfer

Embryo Transfer

The Benefits & Drawbacks of Fresh & Frozen Embryo Transfer

Advantages of Fresh Embryo Transfer:

  • The waiting time for fresh embryo transfer is shorter as embryos are transferred soon after fertilization.
  • The embryos are not subjected to the stress of freezing & thawing.
  • Fresh cycle involves the process of ovarian stimulation, which can result in a receptive endometrial lining, if the women is not hyper – responded.

Disadvantages of Fresh Embryo Transfer

  • Ovarian stimulation during fresh cycles may result in OHSS (ovarian hyperstimulation syndrome), a potentially serious condition marked by enlarged & painful ovaries.
  • Fresh transfer is time critical & need to be synchronized with the natural menstrual cycle, providing limited flexibility in terms of timing.

Advantages of Frozen embryo Transfer

  • FET provides a couple who have encountered challenging situations like cancer treatments with the opportunity to have children once their treatments are successfully completed.
  • Reduced risk of ovarian hyperstimulation.
Disadvantages of frozen embryo transfer

  • Not every embryo can withstand the freezing & thawing process, which could lead to a reduced no. of embryos available for transfer.
  • Going through frozen embryo transfer can be quite time consuming.

Factors to consider when deciding between fresh or frozen embryo transfer

  • Personal health
  • Timing flexibility
  • Success rate

NOTE: REVIVA IVF & Fertility Clinic in Chandigarh provides advanced fertility preservation methods. Our dedicated healthcare team serves exceptional care with precision & expertise in reproductive healthcare. For specialized assistance with embryo transfer, reach out REVIVA IVF & fertility Clinic

For more information contact us at :9915004407

To Get Started on Your Journey Today

Give Us a Call

Decoding The Signs of Bad Egg Quality – A deep Dive into Fertility