Oocyte Donation:
Eggs

Donor Eggs are required in those cases where the female partner cannot produce her own eggs, or the eggs are not of appropriate quality. There is an increasing demand for egg donor services nowadays.

1. Menopausal females.
2. Premature Ovarian Failure.
3. Gonadal Dysgenesis
4. Patients with repeated IVF failures due to poor quality eggs
5. Those with decreased ovarian reserve due to any cause.
6. fertility as a result of cancer treatment.

• Donor Selection
• Ovulation Induction
• Uterus Preparation
• Fertilization

A donor may only be accepted if they meet the rigorous screening criteria:-

1. Must be under 30 years of age.
2. Must be within a normal weight range.
3. Hormone levels must be within the normal range.
4. Have no personal /family history of inherited illness or abnormalities.
5. Must be nonsmokers.
6. Free of sexually transmitted disease, HIV-1, VDRL, Hepatitis.
7. In addition, their eggs must be of sufficient quality to give the recipient the best chance of conceiving.

• Recipient GnRH agonist downregulation started.
• Donor GnRH downregulation started.

• Despite the shortage of donor eggs, Donors may only be accepted if they meet the rigorous screening criteria.
• After periods, recipients’ oral estrogens started to make good endometrium. This is given for a minimum period of 12-14 days.
• After periods the donor started with injections for follicular stimulation.

• Donor oocyte retrieval is done appropriately, followed by IVF/ICSI with the recipient’s husband’s sperms.
• Recipients progesterone started along with estradiol, and embryo transfer is done. Serum pregnancy testing is done 12 days post-transfer.